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  • Knockdown of TSP-4 alleviates MI/RI-induced myocardial injury and improves brain inflammation by enhancing blood-brain barrier stability
    TSP-4的敲除通过增强血脑屏障稳定性减轻心肌炎引起的 myocardial损伤并改善大脑炎症反应

    Jiahao Feng,Yanfeng Lu,Haoyu Wu et al.

    Human molecular genetics. 2025 Mar 29:ddaf037. DOI:10.1093/hmg/ddaf037
  • The role of CSNK1A1 and its de novo mutations in infantile spasms syndrome
    CSNK1A1及其全新突变在婴儿痉挛症中的作用

    Decheng Ren,Zhenxi Yang,Juan Hu et al.

    Human molecular genetics. 2025 Mar 28:ddaf030. DOI:10.1093/hmg/ddaf030
  • Expression of Concern: Cowden syndrome-associated germline SDHD variants alter PTEN nuclear translocation through SRC-induced PTEN oxidation
    关注表达：与Cowden综合征相关的种系SDHD变异通过SRC诱导的PTEN氧化改变PTEN核转位

    Human molecular genetics. 2025 Mar 28:ddaf042. DOI:10.1093/hmg/ddaf042
  • Expression of Concern: Naturally occurring germline and tumor-associated mutations within the ATP-binding motifs of PTEN lead to oxidative damage of DNA associated with decreased nuclear p53
    关注表达：PTEN内的ATP结合基序中天然发生的生殖系和肿瘤相关突变导致与核p53减少相关的DNA氧化损伤

    Human molecular genetics. 2025 Mar 28:ddaf041. DOI:10.1093/hmg/ddaf041
  • New insights into tumor microenvironment and HPV integrations in cervical cancer pathogenesis revealed by single-cell transcriptome data
    单细胞转录组数据揭示宫颈癌发病机制中肿瘤微环境和HPV整合的新见解

    Xi Zeng,Fang Peng,Ziying Wang et al.

    Human molecular genetics. 2025 Mar 27:ddaf027. DOI:10.1093/hmg/ddaf027
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