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Glycosylation Modification Balances the Aqueous Solubility of Lipidated Peptides and Facilitates Their Biostability

糖基化修饰平衡脂肽的水溶性并促进其生物稳定性

Guozhen Dong,Liyan Gong,Qianqian Zhang et al.

Bioconjugate chemistry. 2025 Apr 9. DOI:10.1021/acs.bioconjchem.5c00057

In Vivo Interrogation of Cell-Penetrating Peptide Function: Accumulation in Tumors and the Potential as a Specific PET Probe

细胞穿透肽功能的体内检测：在肿瘤中的累积及其作为特定PET探针的潜力

Zhan Si,Lulu Tian,Hongxin Zhou et al.

Bioconjugate chemistry. 2025 Apr 9. DOI:10.1021/acs.bioconjchem.5c00128

Mitigating Cannabidiol's Non-Selective Cytotoxicity via Subcellular Organelle Targeting: Exploring Mitochondrial Targeting Potential

通过亚细胞器靶向缓解大麻二酚的非选择性细胞毒性：探索线粒体靶向潜能

Genglian Liu,Ru Li,Jingwei Gao et al.

Bioconjugate chemistry. 2025 Apr 8. DOI:10.1021/acs.bioconjchem.5c00012

Discovery of a Novel ADC for Multifunctional Theranostics: From Vascular Normalization to Synergistic Therapy

用于诊疗一体化的新型多功能抗体偶联药物发现：从血管正常化到协同治疗

Yanchen Li,Jin Wang,Tingting Liu et al.

Bioconjugate chemistry. 2025 Apr 8. DOI:10.1021/acs.bioconjchem.5c00116

In Silico-Driven THIOMAB Approach for Stable PROTAC Conjugates by Docking Payloads in Antibody Cavities

基于抗体空腔对接负载物的THIOMAB稳定PROTAC连接物的计算机辅助设计方法学研究

Shiwei Song,Yahui Liu,Jiaqi Liu et al.

Bioconjugate chemistry. 2025 Apr 8. DOI:10.1021/acs.bioconjchem.4c00588

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