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Pharmacokinetic/Pharmacodynamic Modeling of the Acute Heart Rate Effects of Delta-9 Tetrahydrocannabinol and Its Major Metabolites After Intravenous Injection in Healthy Volunteers

大麻酚和主要代谢产物对健康志愿者静脉注射后急性心率影响的药代动力学/药效学模型研究

W R Wolowich,R Greif,L Theiler et al.

European journal of drug metabolism and pharmacokinetics. 2025 Apr 5. DOI:10.1007/s13318-025-00941-8

Influence of Polymorphisms in Pharmacokinetics-Related Genes on the Areas Under the Plasma Concentration-Time Curves of Doxorubicin and Doxorubicinol in Patients with Diffuse Large B-Cell Lymphoma Receiving CHOP Therapy

药动学相关基因多态性对CHOP方案治疗弥漫大B细胞淋巴瘤患者阿霉素及其代谢产物阿霉索林血药浓度曲线下面积的影响

Keigo Saito,Takenori Takahata,Junichi Nakagawa et al.

European journal of drug metabolism and pharmacokinetics. 2025 Apr 4. DOI:10.1007/s13318-025-00940-9

Minimal Physiologically-Based Pharmacokinetic Modeling of Atenolol and Metoprolol Absorption in Malnourished Rats

应用于营养不良大鼠阿替洛尔和美托洛尔吸收的最小生理药代动力学模型研究

Fatma Kir,Selma Sahin,William J Jusko

European journal of drug metabolism and pharmacokinetics. 2025 Apr 2. DOI:10.1007/s13318-025-00943-6

In Vitro and In Vivo Pharmacokinetic Characterization of 7-Hydroxymitragynine, an Active Metabolite of Mitragynine, in Sprague-Dawley Rats

7-羟基醉麻藤碱的体内外药代动力学特征（在Sprague-Dawley大鼠中的研究）

Yi-Hua Chiang,Siva Rama Raju Kanumuri,Michelle A Kuntz et al.

European journal of drug metabolism and pharmacokinetics. 2025 Mar 22. DOI:10.1007/s13318-025-00939-2

Development of a Physiologically-Based Pharmacokinetic Model for Quantitative Interpretation of Transdermal Drug Delivery of Rotigotine, a Dopamine Agonist for Treating Parkinson's Disease

罗替戈汀的生理药代动力学模型的发展，用于定量解释经皮给药过程。作为一种多巴胺激动剂，罗替戈汀可用于治疗帕金森病。

Ji-Hun Jang,Seung-Hyun Jeong

European journal of drug metabolism and pharmacokinetics. 2025 Mar 15. DOI:10.1007/s13318-025-00938-3

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