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Visualization of calpain-1 activation during cell death and its role in GSDMD cleavage using chemical probes

利用化学探针可视化细胞死亡过程中钙蛋白酶-1的激活及其在GSDMD裂解中的作用

Natalia Horbach,Małgorzata Kalinka,Natalia Ćwilichowska-Puślecka et al.

Cell chemical biology. 2025 Mar 25:S2451-9456(25)00068-6. DOI:10.1016/j.chembiol.2025.03.002

Targeted degradation of CDK9 potently disrupts the MYC-regulated network

CDK9的靶向降解有力地破坏了MYC调节网络

Mohammed A Toure,Keisuke Motoyama,Yichen Xiang et al.

Cell chemical biology. 2025 Mar 25:S2451-9456(25)00067-4. DOI:10.1016/j.chembiol.2025.03.001

Epigenetic fluidity meets phenotypic malleability in intestinal epithelial cells

肠上皮细胞中的表观遗传流动性遇上了表现型可塑性

Swarnabh Bhattacharya,Ramesh A Shivdasani

Cell chemical biology. 2025 Mar 20;32(3):389-391. DOI:10.1016/j.chembiol.2025.02.007

Disrupting neuron-tumor networking connections

干扰神经元-肿瘤的网络连接

Cheng-En Shen,Alesandra S Echeandía Marrero,Yuan Pan

Cell chemical biology. 2025 Mar 20;32(3):386-388. DOI:10.1016/j.chembiol.2025.02.006

Lipid it up: Freed fats drive ferroptosis

脂质激增：自由脂肪驱动铁死亡

Madison S Mortensen,Jennifer L Watts

Cell chemical biology. 2025 Mar 20;32(3):384-385. DOI:10.1016/j.chembiol.2025.02.008

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